Functional clustering of differentially expressed genes of hMSC-OP, hMSC-old and hMSC-senescent when compared to hMSC-C.

arrows pointing downward = at least 2fold reduced expression in comparison to hMSC-C; arrows pointing upward = at least 2fold enhanced expression in comparison to hMSC-C;W = gene associated with WNT signaling;B = gene associated with BMP signaling;* = probesets that refer to the gene are not identical in the indicated comparisons.

向下箭头：相较于hMSC-C，基因表达量至少下调2倍；向上箭头：相较于hMSC-C，基因表达量至少上调2倍；W：与WNT信号通路相关的基因；B：与BMP信号通路相关的基因；*：在指定的比较分析中，靶向对应基因的探针组（probesets）并不完全一致。