Computation times for gene and gene-set analyses.

‘Factor’ indicates the increase in computation time relative to MAGMA-main. MAGMA computation times for gene-set analysis include both self-contained and competitive tests. All analyses were run on the same system.a up to 100,000 permutationsb up to 10,000 permutationsc covariates are PCs used for stratification correctiond 1,000 permutationse did not completef 5,000 permutations, 1,000 replicationsg 10,000 replicates, 10,000 bootstrapsComputation times for gene and gene-set analyses.'因子（Factor）'指相较于MAGMA-main的计算耗时增幅。MAGMA用于基因集分析（gene-set analysis）的计算耗时包含自包含检验（self-contained test）与竞争检验（competitive test）两类。所有分析均在同一计算系统上完成。 a）最大可执行100,000次置换（permutation） b）最大可执行10,000次置换 c）协变量为用于分层校正的主成分（PC, Principal Components） d）1,000次置换 e）未完成运行 f）5,000次置换，1,000次重复实验 g）10,000次重复实验与10,000次自举（bootstrap） 基因与基因集分析的计算耗时情况。