Analysis of small RNAs in EGFP-Neo knock-in mouse testes. Mus musculus

Piwi-interacting RNAs (piRNAs) are 25-32 nt small RNAs bound to Piwi proteins. To know whether the piRNA are generated from reporter genes inserted into piRNA cluster, we sequenced small RNAs from knockin mouse testes and analyzed piRNAs.

Piwi互作RNA（Piwi-interacting RNAs，piRNAs）是一类长度为25~32 nt、结合Piwi蛋白的小RNA。为探究piRNAs是否由插入piRNA基因簇的报告基因所产生，我们对敲入小鼠的睾丸小RNA进行了测序，并对piRNAs开展了分析。