Supporting Information for: Dynamic Stabilization of HMG-CoA Reductase through Optimized Flavonoid Scaffolds: A Mechanistic Investigation of Kaempferol and Apigenin Analogues

Supporting Information for: Dynamic Stabilization of HMG-CoA Reductase through Optimized Flavonoid Scaffolds: A Mechanistic Investigation of Kaempferol and Apigenin Analogues By Yoshua B. Mtulo, James E. Mgaya, Anthony A. Tepeli, Andrew S. Paluch and Lucas Paul* *[e-mail] Submitted to ChemistrySelect, 13 February 2026 ADMET This folder includes five files, each containing the SMILES string used for ADMET analysis. Within the folders " kaempferol" and "apigenin" we provide tabulated spreadsheets of the respective Ligand SMILES and CHEMBL ID.配套支持信息： 基于优化黄酮骨架的HMG-CoA还原酶（HMG-CoA Reductase）动态稳定化：山奈酚与芹菜素类似物的机制研究 作者：Yoshua B. Mtulo、James E. Mgaya、Anthony A. Tepeli、Andrew S. Paluch 及 Lucas Paul* *通讯作者邮箱：[e-mail] 本文已于2026年2月13日提交至《ChemistrySelect》期刊。 ADMET分析 本文件夹包含5个文件，每个文件均收录了用于ADMET分析的简化分子线性输入规范（SMILES）字符串。 在“kaempferol（山奈酚）”与“apigenin（芹菜素）”对应文件夹中，我们提供了各自配体（Ligand）的SMILES字符串与CHEMBL ID的制表电子表格。