Ubiquitination-directed protein degradation is important for tumor initiation and maintenance in many cancers. E3 ligases containing HECT domains are emerging as new therapeutic targets. In contrast t

NIAID Data Ecosystem40

Changes in mRNA/protein expression and signaling pathways in in vivo passaged mouse ovarian cancer cells

卵巢癌分子机制

肿瘤RNA-seq分析

The cure rate for late stage epithelial ovarian cancer (EOC) has not significantly improved over several decades. New and more effective targets and treatment modalities are urgently needed. RNA-seq a

NIAID Data Ecosystem50

The whole transcriptome expression profiling of human SKOV3 comparison between control and CtBP1 KD, ctbp2 KD and CTBP1/2 DKD.

卵巢癌分子机制

转录组功能分析

To discover the regulatory role of CTBP1/2 in high grade serous ovarian cancer, The full cDNA was extracted from SKOV3 shRNA control and CtBP1/2 knockdown and then compared the expression profiles

NIAID Data Ecosystem40

Changes in follistatin levels by BRCA1 may serve as a regulator of ovarian carcinogenesis

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