Summary of predominant epitopes recognized by anti-E Abs in human sera after DENV infection.

*Primary or secondary infection was determined by PRNT50 as described in Methods.**DF, dengue fever according to WHO case definition [2].†Predominant epitopes recognized by anti-E Abs in polyclonal human sera were identified by dot blot assay and residues with severe (reduction in R.I.≥70%) or moderate (50%≤reduction in R.I.

* 原发性或继发性感染通过方法部分所述的PRNT50（Plaque Reduction Neutralization Test 50%，50%噬斑减少中和试验）进行判定。
** DF即登革热，符合世界卫生组织（World Health Organization, WHO）的病例定义[2]。
† 多克隆人血清中的抗E抗体（anti-E antibodies, anti-E Abs）所识别的优势表位通过斑点印迹试验（dot blot assay）进行鉴定，且残基的影响程度分为重度（相对指数[Relative Index, R.I.]降低≥70%）或中度（50%≤相对指数降低）。