Vaccination of poultry against highly pathogenic avian influenza – part 1. Available vaccines and vaccination strategies. Annex A–Supplementary information on ToR 1 data

Table A.1 - Available vaccines for HPAI in poultry. The table includes information on vaccine characteristics such as HA seed strain, vaccine dosage and administration route, target species, authorisation status, challenge strain, duration of immunity and source of information. Table A.2 - Challenge experiments. The table includes data extracted from 28 selected studies from literature on challenge experiments. The data was used to quantify VE_S, VE_m, VE_shand VE_s,shfor each vaccine assessed within each study. For each value of VE_s,sh the probability R_vac &lt; 1 was estimated to infer the probability of the vaccine to potentially stop transmission in vaccinated birds (VE_T). Table A.3 - Transmission experiments. The table includes data extracted from 12 studies from the literature, data was used from the unvaccinated and vaccinated groups to quantify VE_S, VE_m, VE_sh and VE_s,sh for each vaccine assessed within each study; the estimated R values for the unvaccinated (R_unv) and vaccinated (R_vac) groups were also extracted. The R_vac values were used to create a binomial variable classifying whether the vaccine could stop transmission (R &lt; 1) or not.表A.1——家禽高致病性禽流感（Highly Pathogenic Avian Influenza, HPAI）可用疫苗。该表格涵盖疫苗相关特性信息，包括血凝素（Hemagglutinin, HA）种毒株、疫苗接种剂量与接种途径、目标畜禽种类、审批授权状态、攻毒毒株、免疫持续时长以及信息来源。表A.2——攻毒试验。该表格收录了从28篇精选文献中提取的攻毒试验数据，用于量化每项研究中所评估的各款疫苗的疫苗效力（Vaccine Efficacy, VE）相关指标：VE_S、VE_m、VE_sh及VE_s,sh。针对每一组VE_s,sh数值，研究人员估算了免疫组R_vac < 1的概率，以此推断疫苗阻断免疫禽群病毒传播的潜在效力（即VE_T）。表A.3——传播试验。该表格收录了从12篇公开文献中提取的相关数据，研究人员从未免疫组与免疫组的试验数据中，量化每项研究中所评估的各款疫苗的VE_S、VE_m、VE_sh及VE_s,sh；同时提取了未免疫组（R_unv）与免疫组（R_vac）的估算R值，并以R_vac值构建二分类变量，用以划分疫苗是否可阻断病毒传播（即R < 1）。