Antimicrobial activity of alvinellacin.

Assays were performed against bacteria routinely used for antimicrobial assays or having a medical incidence, and against the scarce hydrothermal strains (asterisk*) cultivable under the conditions of a microbial assay. The minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) are expressed as final concentration in µM. > denotes no activity detected at the given concentration. The MBC and MIC values are the same, indicating that the bacterial growth inhibition is due to the killing of bacteria.