Antimicrobial activity of alvinellacin.

Assays were performed against bacteria routinely used for antimicrobial assays or having a medical incidence, and against the scarce hydrothermal strains (asterisk*) cultivable under the conditions of a microbial assay. The minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) are expressed as final concentration in µM. > denotes no activity detected at the given concentration. The MBC and MIC values are the same, indicating that the bacterial growth inhibition is due to the killing of bacteria.本实验针对常规用于抗菌活性检测或具有临床相关性的细菌，以及可在微生物实验条件下培养的稀有热液菌株（标记为星号*）展开。实验测定了最低抑菌浓度（minimal inhibitory concentration, MIC）与最低杀菌浓度（minimal bactericidal concentration, MBC），数值均以微摩尔（µM）作为最终浓度单位。符号‘>’表示在给定浓度下未检测到抗菌活性。当MBC与MIC数值一致时，表明对细菌生长的抑制作用源于对细菌的直接杀灭。