Additional file 1 of Gut microbiota from coronary artery disease patients contributes to vascular dysfunction in mice by regulating bile acid metabolism and immune activation

Additional file 1. Table S1 The bile acids profile in the faeces; Table S2 The bile acids profile in the serum; Table S3 Statistics for the metagenomic shotgun sequencing data of mice; Table S4 The assembly statistics of metagenomics data; Table S5 The significantly altered metagenomic pathways between Con and CAD; Table S6 Species abundance with significant differences between Con and CAD; Table S7 Differential expression of genes (DEGs) between the Con (n = 3) and CAD (n = 3) group in the liver; Table S8 Differential expression of genes (DEGs) between the Con (n=3) and CAD (n = 3) group in the ileum; Table S9 Inflammatory factors levels associated with cardiovascular disease between the GF, Con and CAD groups in the serum; Table S10 Primers for RT-PCR.

附加文件1：表S1 粪便胆汁酸谱；表S2 血清胆汁酸谱；表S3 小鼠宏基因组鸟枪法测序（metagenomic shotgun sequencing）数据统计；表S4 宏基因组数据组装统计；表S5 对照组（Control, Con）与冠状动脉疾病（Coronary Artery Disease, CAD）组间存在显著差异的宏基因组通路；表S6 对照组与冠状动脉疾病组间具有显著差异的物种丰度；表S7 肝脏组织中对照组（n=3）与冠状动脉疾病组（n=3）的差异表达基因（DEGs）；表S8 回肠组织中对照组（n=3）与冠状动脉疾病组（n=3）的差异表达基因（DEGs）；表S9 无菌小鼠（Germ-free, GF）、对照组与冠状动脉疾病组血清中与心血管疾病相关的炎症因子水平；表S10 逆转录聚合酶链反应（RT-PCR）引物。