Characteristics of participants by L. reuteri consumption.

1 Differences between group numbers tested with Chi2 test2 Differences between group means tested with Student’s t-test3 % compliance = (lozenges consumed/ lozenges expected to be consumed)*1004 Difference between the test and placebo group were analyzed by non-parametric statistics (The Mann–Whitney U-test). Numbers are expressed as log10 valuesCFU, colony-forming unit; CI, confidence intervalCharacteristics of participants by L. reuteri consumption.1. 采用卡方检验（Chi2 test）比较各组计数资料的组间差异 2. 采用学生t检验（Student’s t-test）比较各组均值的组间差异 3. 依从性百分比(%) =（实际服用含片数/预计服用含片数）×100 4. 试验组与安慰剂组的差异采用非参数统计方法（曼-惠特尼U检验，Mann–Whitney U-test）进行分析，数据以log10值表示 CFU：菌落形成单位（colony-forming unit）；CI：置信区间（confidence interval） 按罗伊氏乳杆菌（L. reuteri）摄入情况统计的受试者特征。