Data from: Hepatitis B vaccination coverage, knowledge and socio-demographic determinants of uptake in high-risk public safety workers in Kaduna State, Nigeria: a cross-sectional survey

Objectives: To estimate hepatitis B vaccination (HBVc) coverage, and knowledge and socio-demographic determinants of full-dose uptake in Federal Road Safety Corps (FRSC) members, Kaduna State, Nigeria in order to inform relevant targeted vaccination policies. Design: A cross-sectional survey of FRSC members, Kaduna Sector Command. Settings: Six randomly-selected Unit Commands under Kaduna Sector Command, Kaduna State, Nigeria. Participants: Pilot-tested structured self-administered questionnaire was administered to 341 participants aged 18 years and above with ≥6 months of service between 17th June and 22nd July, 2015. Excluded were FRSC members in Road Safety (RS) 1 Zonal Command headquarters as the Zonal Command includes other States beyond the study scope. Primary Outcome: HBVc status of participants categorized as ‘not vaccinated’ for uptake of <3 doses and ‘vaccinated’ for uptake of ≥3 doses. Analysis: Descriptive analysis estimated HBVc coverage while logistic regression ascertained associations. Results: Most participants were males, aged 30-39 years, with 3-10 years of service, and of Marshal cadre. HBVc coverage was 60.9% for ≥1 dose and 30.5% for ≥3 doses. Less than 47% of participants scored above the mean knowledge score for hepatitis B virus (HBV) and HBVc. Female sex (AOR 2.28, 95% CI 1.15-4.52, p<0.05), perceiving there to be an occupational risk of exposure to HBV (AOR 2.86, 95% CI 1.06-7.70, p<0.001), and increasing HBVc knowledge (AOR 2.68, 95% CI 1.83-3.92, p<0.001) were independent predictors of full-dose HBVc in FRSC members, Kaduna Sector Command. Conclusions: HBVc coverage and knowledge are poor among FRSC members, Kaduna Sector Command. Educational intervention, geared towards improving FRSC members’ knowledge of HBVc and perception of risk of occupational exposure to HBV, is recommended for these vulnerable public safety workers. Such enlightenment could be a cheap and easy way of improving HBVc coverage in the study population.

研究目的：评估尼日利亚卡杜纳州联邦道路安全队（Federal Road Safety Corps, FRSC）成员的乙型肝炎疫苗（hepatitis B vaccination, HBVc）接种覆盖率，以及全程接种的认知与社会人口学影响因素，为制定针对性疫苗接种政策提供依据。
研究设计：针对卡杜纳州分区司令部联邦道路安全队成员开展横断面调查。
研究场景：选取尼日利亚卡杜纳州卡杜纳分区司令部下辖6个随机抽取的分队司令部作为调研现场。
研究对象：2015年6月17日至7月22日期间，向341名年满18周岁、服役时长≥6个月的对象发放经过预试验的结构化自填式问卷。排除对象为道路安全1分区司令部总部的联邦道路安全队成员，因该分区司令部覆盖研究范围以外的其他州。
主要结局指标：将参与者的乙型肝炎疫苗接种情况分为两类：接种剂量<3剂者归类为"未接种"，接种剂量≥3剂者归类为"已接种"。
数据分析：采用描述性分析估算乙型肝炎疫苗接种覆盖率，通过Logistic回归分析确定相关关联。
研究结果：大部分参与者为男性，年龄处于30~39岁区间，服役年限3~10年，属Marshal职级。乙型肝炎疫苗接种覆盖率为：接种≥1剂者占60.9%，全程接种（≥3剂）者占30.5%。仅有不到47%的参与者乙型肝炎病毒（hepatitis B virus, HBV）与乙型肝炎疫苗接种相关认知得分高于均值。多因素Logistic回归分析显示，女性（调整后优势比[AOR] 2.28，95%置信区间[CI] 1.15~4.52，p<0.05）、认为存在乙型肝炎病毒职业暴露风险（AOR 2.86，95%CI 1.06~7.70，p<0.001）以及乙型肝炎疫苗接种认知水平提升（AOR 2.68，95%CI 1.83~3.92，p<0.001）是卡杜纳分区司令部联邦道路安全队成员完成全程乙型肝炎疫苗接种的独立预测因素。
研究结论：卡杜纳州分区司令部联邦道路安全队成员的乙型肝炎疫苗接种覆盖率与相关认知水平均偏低。建议针对这类易暴露的公共安全从业人员开展教育干预，以提升其对乙型肝炎病毒与乙型肝炎疫苗接种的认知水平，以及对乙型肝炎病毒职业暴露风险的认知。此类宣教活动可作为低成本、易实施的手段，提升本研究人群的乙型肝炎疫苗接种覆盖率。