A Virtual Library for Behavioral Performance in Standard Conditions – Experiment 10 Q29 Effect of CP809101 (5HT2C agonist) on the expression of sensitization and compulsive checking in an open field bordered by a low ledge

Beyond their specific experiment, video records of behavior have future value; for example, as inputs for new experiments or for yet unknown types of analysis of behaviorsimilar to tissue or blood sample banks in life sciences where clinically-derived or otherwise well-described experimental samples are stored to be available for some unknown potential future purpose. <br>Research using an animal model of obsessive-compulsive disorder employed a standardized paradigm where the behavior of rats in a large open field was video recorded for 55 min on each test. From 43 experiments, there are 19,976 such trials that amount to over 2 years of continuous recording. In addition to videos, there are two video-derived raw data objects: XY locomotion coordinates, and plots of animal trajectory. To motivate future use, the three raw data objects are annotated with a general schemaone that abstracts the data records from their particular experiment while providing, at the same time a detailed list of independent variables bearing on behavioral performance. The raw data objects are deposited as 43 datasets but constitute, functionally, a library containing one large dataset. <br>Size and annotation schema give the library high re-use potential: in applications using machine learning techniques, statistical evaluation of subtle factors, simulation of new experiments, or as educational resource. Ultimately, the library can serve both as the seed and the test bed to create a machine searchable virtual library of linked open datasets for behavioral performance in defined conditions.

除却其特定实验本身的应用价值外，行为视频记录还具备远期应用潜力：例如可作为新实验的输入数据，或用于未来尚未被定义的行为分析类型——这与生命科学领域的组织或血液样本库类似：后者将临床来源或经完善描述的实验样本妥善存储，以备未来未知的潜在研究需求。

本数据集基于强迫症（Obsessive-Compulsive Disorder, OCD）动物模型展开研究，采用标准化实验范式：在大型旷场装置中，对大鼠的行为进行单次55分钟的视频录制，每一次测试均生成对应记录。本数据集涵盖来自43项独立实验的19976次测试记录，累计连续录制时长超过2年。除原始视频文件外，还包含两类由视频衍生的原始数据对象：大鼠的XY运动坐标，以及动物运动轨迹图。为促进该数据集的后续复用，三类原始数据对象均采用通用模式架构（schema）进行标注：该架构可将数据记录从其所属的特定实验中抽象出来，同时提供与动物行为表现相关的自变量详细列表。尽管原始数据对象以43个独立数据集的形式提交存储，但从功能层面而言，其整体构成一个包含单一大型数据集的资源库。

数据集的规模与标注模式架构赋予其极高的复用潜力：可应用于机器学习技术相关研究、细微影响因素的统计评估、新实验模拟，亦可作为教学资源使用。从长远来看，该资源库既可作为构建此类资源库的起点，也可作为测试平台，最终用于创建支持机器检索的关联开放数据集虚拟库，覆盖特定条件下的动物行为表现数据。