Spontaneous outer retinal layer recovery in a case of hypertensive choroidopathy secondary to pre-eclampsia: a multimodal evaluation

ABSTRACT A 26-year-old woman presented at 28 weeks gestation with hypertensive choroidopathy associated with pre-eclampsia. Fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography (SD-OCT), fluorescein angiography, and indocyanine green angiography were performed in both eyes in the immediate postoperative period. SD-OCT images were obtained before delivery and during a 3-month follow-up. Fundus autofluorescence exhibited patchy hyper- and hypoautofluorescent lesions; fluorescein and indocyanine green angiography revealed areas of choroidal ischemia; and SD-OCT showed disorganization of the outer retinal layers and disruption of the ellipsoid zone. After her blood pressure was stabilized, progressive recovery of the outer retinal layer was monitored on SD-OCT.

摘要 一例26岁女性患者于妊娠28周时因子痫前期（pre-eclampsia）并发高血压性脉络膜病变（hypertensive choroidopathy）就诊。研究人员于术后即刻对双眼行眼底照相（fundus photography）、眼底自发荧光（fundus autofluorescence）、spectral-domain光学相干断层扫描（SD-OCT）、荧光素眼底血管造影（fluorescein angiography）及吲哚菁绿血管造影（indocyanine green angiography）检查，并于分娩前及3个月随访期间采集了SD-OCT影像。眼底自发荧光可见斑驳状高、低自发荧光病灶；荧光素及吲哚菁绿血管造影显示脉络膜缺血区域；SD-OCT可见视网膜外层结构紊乱及椭圆体带（ellipsoid zone）中断。在患者血压得到平稳控制后，通过SD-OCT监测到视网膜外层结构逐步恢复。