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Eastern oyster (Crassostrea virginica) gonad DNA methylation data and analysis

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Figshare2020-03-19 更新2026-04-08 收录
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https://figshare.com/articles/General_DNA_methylation_patterns_and_environmentally-induced_differential_methylation_in_the_eastern_oyster_Crassostrea_virginica_/11923479/3
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Epigenetic modification, specifically DNA methylation, is one possible mechanism for transgenerational plasticity. Before inheritance of methylation patterns can be characterized we need a better understanding of how environmental change modifies the parental epigenome. Specifically, methylation patterns should be understood in reproductive tissue. We examined the effect of ocean acidification on Eastern oyster (<i>Crassostrea virginica</i>) reproductive tissue.<br>The associated Github repository can be found here: https://github.com/epigeneticstoocean/paper-gonad-meth<br>This repository is associated with the manuscript "General DNA methylation patterns and environmentally-induced differential methylation in the eastern oyster (<i>Crassostrea virginica</i>)" on bioRXiv: https://www.biorxiv.org/content/10.1101/2020.01.07.897934v1

表观遗传修饰(epigenetic modification),尤其是DNA甲基化(DNA methylation),是跨代可塑性(transgenerational plasticity)的潜在机制之一。在对甲基化模式的遗传特性开展表征工作前,我们需要更深入地阐明环境变化如何改变亲本表观组(parental epigenome)。具体而言,需优先在生殖组织(reproductive tissue)中解析甲基化模式。本研究针对海洋酸化(ocean acidification)对东部牡蛎(*Crassostrea virginica*)生殖组织的影响展开了探究。 相关GitHub代码仓库可通过以下链接获取:https://github.com/epigeneticstoocean/paper-gonad-meth 该仓库关联的bioRxiv预印手稿为《东部牡蛎(*Crassostrea virginica*)的通用DNA甲基化模式与环境诱导的差异甲基化》,链接为:https://www.biorxiv.org/content/10.1101/2020.01.07.897934v1
提供机构:
Yaamini Venkataraman
创建时间:
2020-03-19
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