Blood pressure levels and associated factors among pregnant women of the MINA-Brazil Study

Abstract The scope of this study was to investigate the factors associated with blood pressure levels among pregnant women participating in the MINA-Brazil Study, registered in the Family Health Strategy in Cruzeiro do Sul in the Western Brazilian Amazon. Multiple linear regression models were used, adopting a level of significance of 5%. The majority of pregnant participants were less than 24 years of age, 44% were primigravidae, and 59.1% had excessive weekly gestational weight gain. The frequency of hypertension was 0.7%. Factors positively associated with systolic blood pressure levels in pregnancy were pre-pregnancy body mass index (β = 0.984, CI95%: 0.768-1.200), and weekly gestational weight gain (β = 6.816, CI95%: 3.368-10.264). Diastolic blood pressure levels in pregnancy were positively associated with maternal age (β = 0.111, CI95%: 0.002-0.221), maternal schooling (β = 2.194, CI95%: 0.779-3.609), pre-pregnancy body mass index (β = 0.589, CI95%: 0.427-0.751), and weekly gestational weight gain (β = 3.066, CI95%: 0.483-5.650). These findings stress the importance of the role of antenatal care to prevent hypertensive disorders during pregnancy.

摘要 本研究旨在探究参与巴西MINA研究（MINA-Brazil Study）的孕妇血压水平的相关影响因素，该研究的受试者均招募自巴西亚马孙西部克鲁塞罗杜尔市的家庭健康战略（Family Health Strategy）登记人群。本研究采用多元线性回归模型，设定显著性水平为5%。参与本研究的孕妇大多年龄不足24岁，其中44%为初孕妇（primigravidae），59.1%的孕妇孕期每周体重增长超标。研究人群中高血压检出率为0.7%。妊娠收缩压水平与以下因素呈正相关：孕前体重指数（pre-pregnancy body mass index，β=0.984，95%置信区间：0.768~1.200）及孕期每周体重增长值（β=6.816，95%置信区间：3.368~10.264）。妊娠舒张压水平与以下因素呈正相关：产妇年龄（β=0.111，95%置信区间：0.002~0.221）、产妇受教育程度（maternal schooling，β=2.194，95%置信区间：0.779~3.609）、孕前体重指数（β=0.589，95%置信区间：0.427~0.751）以及孕期每周体重增长值（β=3.066，95%置信区间：0.483~5.650）。本研究结果凸显了产前保健对预防妊娠期高血压疾病的重要意义。