Multi-omics analysis revealing the interplay between gut microbiome and the host following opioid use [RNA-seq]. Multi-omics analysis revealing the interplay between gut microbiome and the host following opioid use [RNA-seq]

To uncover the role of opioid induced dysbiosis in disrupting intestinal homeostasis, we conducted a multi-omics analysis with gut microbial, metabolite and intestinal transcriptomics data Overall design: We identified changes in host gene expression changes following morphine treatment using RNA sequencing

为阐明阿片类药物（opioid）诱导的菌群失调在破坏肠道稳态中的作用，我们开展了涵盖肠道微生物组、代谢组与肠道转录组数据的多组学分析。实验设计概述：我们通过RNA测序（RNA Sequencing）鉴定了吗啡处理后宿主的基因表达变化。