Additional file 3 of Analyses of key genes involved in Arctic adaptation in polar bears suggest selection on both standing variation and de novo mutations played an important role

Additional file 3: Supplementary Table S3. Table including all relevant information at the genes of interest, including nucleotide information, gene location, amino acid information, allele distributions, and predictions of amino acid changes in the sites in which the alternative allele is also found in the giant panda. Red coloured cells indicate sites in which amino acid changes may have a functional influence according to at least one of the three tests: Polyphen-2, SIFT, or PROVEAN. D/D represents homozygous derived, D/A represents heterozygous derived and ancestral, A/A represents homozygous ancestral.

附加文件3：补充表S3。本表格收录了目标基因的全部相关信息，涵盖核苷酸信息、基因定位信息、氨基酸信息、等位基因分布情况，以及变异等位基因亦存在于大熊猫中的位点的氨基酸变异预测结果。标红单元格代表经Polyphen-2、SIFT或PROVEAN三种检测工具中至少一种判定，其氨基酸变异可能具有功能性影响的位点。D/D 代表纯合衍生型，D/A 代表杂合衍生-祖先型，A/A 代表纯合祖先型。