Supplementary Material for "Thermodynamic Reaction Control of Nucleoside Phosphorolysis"

This is the supplementary material for our publication "Thermodynamic Reaction Control of Nucleoside Phosphorolysis". The .pdf file contains the supplementary information: Author Contributions, Figure S1 and Tables S1-S3. The .zip file contains the raw data, metadata and results from Figure 1, 2, 4 and 5. The .xlsx file contains the apparent transformed values of the reaction enthalpy and entropy of nucleosides <strong>1</strong>-<strong>24</strong> the calculated apparent Gibbs free energies of nucleosides <strong>1</strong>-<strong>24</strong> and the implementation of these values for the calculation of equilibrium conversions of nucleosides <strong>1</strong>-<strong>24</strong> with variable (adjustable) reaction conditions (concentrations of the nucleoside, phosphate and reaction temperature). For the software employed for spectra unmixing, please see doi: 10.5281/zenodo.3243376 and our previous work (doi: 10.3390/mps2030060) as well as its supporting material (doi: 10.5281/zenodo.3333469) for clarification.本材料为我们发表的论文《核苷磷酸解的热力学反应调控》（Thermodynamic Reaction Control of Nucleoside Phosphorolysis）的补充配套材料。其中PDF文件包含补充信息：作者贡献声明、附图S1以及附表S1至S3。压缩包（.zip）收录了图1、图2、图4与图5对应的原始数据、元数据与研究结果。XLSX文件则涵盖核苷1-24的反应焓与反应熵的表观转换值、核苷1-24的计算表观吉布斯自由能，以及利用上述数值开展可变（可调）反应条件（核苷浓度、磷酸盐浓度与反应温度）下核苷1-24的平衡转化率计算的实现方法。如需了解用于光谱解混的软件，请参考DOI：10.5281/zenodo.3243376、我们的前期研究工作（DOI：10.3390/mps2030060）及其配套补充材料（DOI：10.5281/zenodo.3333469）以获取详细说明。