Seroconversion rates in BALB/c mice immunized with purified inactivated EV71.

aPBST = Phosphate Buffered Saline + 0.002% (v/v) Tween 80, buffer base for purified inactivated EV71.Mice were immunized with inactivated virus with or without Alhydrogel at 28, 42 and 56 days post primary immunization. Seroconversion is defined as a neutralizing antibody titre of ≥128.

aPBST为添加0.002%（体积比）吐温80（Tween 80）的磷酸缓冲盐溶液（Phosphate Buffered Saline），是纯化灭活EV71（肠道病毒71型，Enterovirus 71）的缓冲基础液。在初次免疫后的第28、42和56天，使用含或不含Alhydrogel（氢氧化铝佐剂）的灭活病毒对小鼠实施免疫。血清转换的判定标准为中和抗体滴度≥128。