List of seven common hit pathways identified by the three independent approaches.

The additional four common pathways identified not shown correspond to general pathway descriptions (i.e., mtu01100 “Metabolic pathways”, mtu01110 “Biosynthesis of secondary metabolites”, mtu01120 “Microbial metabolism in diverse environments”, and mtu00000 “No Pathway”). Target genes in italics are either in vivo or in vitro essential in the TraSH Essentiality database [21].

本次鉴定得到但未展示的另外4条常见通路，均属于通用通路范畴（即mtu01100「代谢通路（Metabolic pathways）」、mtu01110「次级代谢产物生物合成（Biosynthesis of secondary metabolites）」、mtu01120「多样环境中的微生物代谢（Microbial metabolism in diverse environments）」以及mtu00000「无通路（No Pathway）」）。以斜体标注的靶基因，在TraSH必需性数据库（TraSH Essentiality database）[21]中均为体内（in vivo）或体外（in vitro）必需基因。