Expression data from DLBCL expression study. Expression data from DLBCL expression study

We used microarray data sets to determine concordance of microarray vs qRT-PCR based LCOO cell-of-origin for Diffuse large B-cell Lymphome subtypes. Overall design: Three independent sets of samples were processed and analyzed for a total of 180 samples. Training sets were developed to build and develop a DLBCL classification model. A subsequent validation data set was used to validate the classification model.

本研究采用基因芯片（microarray）数据集，针对弥漫大B细胞淋巴瘤（Diffuse Large B-cell Lymphoma, DLBCL）亚型，评估基于基因芯片法与基于实时定量荧光聚合酶链式反应（quantitative real-time polymerase chain reaction, qRT-PCR）的淋巴瘤细胞起源（Lymphoma Cell of Origin, LCOO）分型结果的一致性。
整体实验设计：本研究共纳入180份样本，分为3个独立样本队列完成处理与分析。其中，我们构建训练集以开发DLBCL分型模型，随后使用独立验证集对该分型模型进行性能验证。