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Information of the four genes showing inverse correlation patterns with Lrp identified by BEST when applied to the 100-gene test set selected from the E. coli microarray compendium.

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Figshare2015-12-02 更新2026-05-11 收录
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All but the first one, gcvB, are in the RegulonDB target set.aGenes displayed here are sorted by the Log Bayes ratio (target gene versus non-target gene).bBlank indicates that the target gene shows the same pattern as the query gene. Negative indicates that the target gene shows the inversed pattern as the query gene.c��X�� indicates that the predicted gene is in the RegulonDB target set.d��X�� indicates that the gene is predicted by CLR as a target gene.eMotif distance is defined as the distance between the start position of the gene and the closest motif in the intergenic region upstream.fEmpirical p-value indicates the significance of conservation in the current motif, which is calculated as proportion of all possible motif locations in the complete E. coli genome that have likelihood ratios comparing between Lrp motif and background higher than that of the current motif.

除首个基因gcvB外,其余基因均属于RegulonDB靶基因集。 a 此处展示的基因按对数贝叶斯比值(靶基因与非靶基因的比值)排序。 b 空白表示该靶基因与查询基因的表达模式一致;负值表示该靶基因与查询基因的表达模式相反。 c ��X�� 表示该预测基因属于RegulonDB靶基因集。 d ��X�� 表示该基因被CLR(Context Likelihood of Relatedness)算法预测为靶基因。 e 基序距离定义为基因起始位点与上游基因间区内最近的基序之间的距离。 f 经验p值用于表征当前基序的保守性显著性,其计算方式为:在完整大肠杆菌(E. coli)基因组中,所有Lrp(Leucine-responsive Regulatory Protein)基序与背景的似然比高于当前基序似然比的潜在基序位点所占的比例。
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2015-12-02
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