Summary ABT-888 and CPT-11 combination treatment in TNBC.

Combinatorial index values (CI) were determined using Calcusyn software from the cell viability data. CI values less than 1 indicate synergy. Each experiment was repeated three times in triplicate.Summary ABT-888 and CPT-11 combination treatment in TNBC.

采用Calcusyn软件，基于细胞活力数据计算得到联合指数值（Combinatorial index, CI）。当CI值小于1时，提示药物组合存在协同作用。每项实验均设置一式三份的平行样本，并独立重复三次。本部分总结了ABT-888与CPT-11联合给药在三阴性乳腺癌（Triple-Negative Breast Cancer, TNBC）中的相关实验结果。