Genome Wide Expression of Mammary Epithelial Populations in Slug (SNAI2) WT vs Slug Null Mice. Mus musculus

This experiment shows differential expression of genes in the luminal, basal and stromal subpopulations from SNAI2+/+ and SNAI2 LacZ/LacZ mammary epithelial cells. Overall design: Luminal, basal and stromal populations were sorted from SNAI2+/+ and SNAI2 LacZ/LacZ mammary epithelial cells based on expression of CD49f and Epcam.

本实验揭示了SNAI2+/+与SNAI2 LacZ/LacZ乳腺上皮细胞的腔上皮、基底上皮及间质亚群中的基因差异表达特征。实验整体设计：基于CD49f与Epcam的表达水平，从SNAI2+/+及SNAI2 LacZ/LacZ乳腺上皮细胞中分选得到腔上皮、基底上皮与间质细胞亚群。