Table1_Echocardiographic myocardial work in pre-adolescent male basketball players: a comparison with cardiopulmonary exercise test-derived aerobic capacity.XLSX

Background: Pressure-strain loop (PSL) analysis provides a novel, less load-dependent non-invasive method to quantify myocardial work and demonstrates a significant correlation with the contractile reserve in adult athletes. We aim to validate PSL-derived markers in characterizing LV function in pre-adolescent basketball players by comparing results before and after the cardiopulmonary exercise test (CPX) and explore its association with CPX-derived aerobic capacity.
Methods: Cardiac morphology and function in 20 pre-adolescent basketball players were assessed at 9.7 years old (9.7 ± 1.1 year) before and after cardiopulmonary exercise testing. Echocardiography was performed in all subjects, including two-dimensional speckle-tracking echocardiography (STE). Simultaneous brachial-cuff-measured blood pressure was recorded to perform PSL analysis.
Results: Nineteen subjects were included in the final analysis. Exercise training in pre-adolescent males was associated with lower global work index (GWI) and global work efficiency (GWE) at rest. GWE at stress was significantly correlated with VO2max and peak O2 pulse (p = 0.0122, r = 0.56; p = 0.00122, r = 0.69, respectively). When indexed by body mass, GWI and GWE both significantly correlated with relative VO2max (p = 0.0086 and 0.0011 respectively, r = 0.58 and 0.69 respectively); GWI and GWE at baseline and stress were all significantly correlated with peak O2 pulse (GWI at baseline, p< 0.0001, r = −0.90; GWE at baseline, p< 0.0001, r = −0.89; GWI at stress, p= 0.0289, r = −0.50; GWE at stress, p< 0.0001, r = −0.83).
Conclusion: PSL-analysis-derived GWI and GWE at rest indexed by body mass are associated with cardiopulmonary exercise test-derived peak oxygen consumption and oxygen pulse in pre-adolescent athletes.

背景：压力-应变环（Pressure-strain loop, PSL）分析是一种新颖的、低负荷依赖的无创定量心肌做功的方法，且与成年运动员的收缩储备能力存在显著相关性。本研究旨在通过对比心肺运动试验（cardiopulmonary exercise test, CPX）前后的检测结果，验证PSL衍生指标在青春期前篮球运动员左心室（Left Ventricle, LV）功能表征中的应用价值，并探索其与CPX衍生的有氧能力的关联。
方法：本研究对20名年龄为9.7±1.1岁（平均9.7岁）的青春期前篮球运动员在心肺运动试验前后的心脏形态与功能进行了评估。所有受试者均接受超声心动图检查，包括二维斑点追踪超声心动图（two-dimensional speckle-tracking echocardiography, STE）。同步记录肱袖带测量的血压，以开展PSL分析。
结果：最终有19名受试者纳入最终分析。青春期前男性运动员的运动训练与静息状态下较低的整体做功指数（global work index, GWI）及整体工作效率（global work efficiency, GWE）相关。负荷状态下的GWE与最大摄氧量（VO2max）及峰值氧脉搏（peak O2 pulse）均存在显著相关性（分别为p=0.0122，r=0.56；p=0.00122，r=0.69）。以体质量校正后，GWI与GWE均与相对VO2max存在显著相关性（分别为p=0.0086、p=0.0011，r=0.58、r=0.69）；基线与负荷状态下的GWI及GWE均与峰值氧脉搏存在显著相关性：基线GWI（p<0.0001，r=-0.90）、基线GWE（p<0.0001，r=-0.89）、负荷GWI（p=0.0289，r=-0.50）、负荷GWE（p<0.0001，r=-0.83）。
结论：经体质量校正的静息状态下PSL分析衍生的GWI与GWE，与青春期前运动员心肺运动试验测得的峰值摄氧量及氧脉搏存在显著关联。