Arthrogryposis multiplex congenita in a family of Red cattle

Arthrogryposis multiplex congenital (AMC) is a syndromic term for a condition characterized by congenital joint contracture (arthrogryposis) of multiple joints involving more than just one part of the body. AMC is usually considered generalized thus involving joints of both the spine and the limbs. AMC is not a specific diagnosis, but rather a descriptive term as it may be caused by a wide range of disorders in the brain, spinal cord, peripheral nerves, muscles and connective tissue as well as space limiting diseases of the pregnant uterus such as oligohydramnios.

先天性多关节挛缩症（Arthrogryposis multiplex congenital, AMC）是一类综合征性术语，用于描述以多关节先天性关节挛缩（arthrogryposis）为特征的病症，其受累范围覆盖身体多个部位的关节。该病症通常被认为属于全身性疾病，可累及脊柱与四肢的关节。先天性多关节挛缩症并非特异性诊断，而是一类描述性术语，其病因涵盖脑、脊髓、周围神经、肌肉及结缔组织的多种病变，同时也可由孕妇子宫内空间受限类疾病引发，例如羊水过少（oligohydramnios）。