Whole genome sequencing of yeast treated with acetaldehyde

The study is aimed at analyzing the mutational landscape of acetaldehyde using the budding yeast as a model system. Acetaldehyde is a potential carcinogen and uncovering the mechanisms driving its mutagenicity would greatly inform treatments of alcohol-associated cancers

本研究以出芽酵母(budding yeast)为模型系统，旨在分析乙醛(acetaldehyde)的突变谱(mutational landscape)。乙醛是一种潜在致癌物，阐明其致突变的作用机制，将为酒精相关癌症的治疗提供重要参考。