The U2 snRNA is a basal component of the major spliceosome, which is responsible for >90% human pre-mRNA splicing. A 5-nucleotide deletion in one of the mouse U2 snRNA genes (Rnu2-8) causes cerebellar
Chaperone-mediated autophagy (CMA) involves the selective lysosomal degradation of cytosolic proteins such as SNCA (synuclein α), a protein strongly implicated in Parkinson disease (PD) pathogenesis.
In vitro assembled 266/297 - 391 tau filaments with KCl (10b) Descriptor: Microtubule-associated protein tau Authors: Lovestam, S, Scheres, S.H.W. Deposit date: 2022-02-10 Release date: 2022-02-23 Las
