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资源简介：
Python script to searche for the shortest pathway between two sequences along a fitness landscape.
应用场景：
创建时间：
2019-01-01
相关数据集
Data from: Fisher's geometrical model of fitness landscape and variance in fitness within a changing environment
The fitness of an individual can be simply defined as the number of its offspring in the next generation. However, it is not well understood how selection on the phenotype determines fitness. In accor
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Efficient escape from local optima in a highly rugged fitness landscape by evolving RNA virus populations
Predicting viral evolution has proven to be a particularly difficult task, mainly owing to our incomplete knowledge of some of the fundamental principles that drive it. Recently, valuable information
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The fitness effect of mutations across environments: Fisher’s geometrical model with multiple optima
When are mutations beneficial in one environment and deleterious in another? More generally, what is the relationship between mutation effects across environments? These questions are crucial to predi
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The fitness landscape of the codon space across environments
Fitness landscapes map the relationship between genotypes and fitness. However, most fitness landscape studies ignore the genetic architecture imposed by the codon table and thereby neglect the potent
DataONE2020-06-24 更新70
Simulation code for Fig S2 from The distribution of epistasis on simple fitness landscapes.
Fitness interactions between mutations can influence a population’s evolution in many different ways. While epistatic effects are difficult to measure precisely, important information is captured by t
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