Study cohort characteristics of cases and controls undergoing primary coronary artery bypass grafting with cardiopulmonary bypass.

Data shown as (%) for dichotomous variables and mean ± standard deviation for continuous variables.
BMI = body mass index; CPB = cardiopulmonary bypass; LVEF = left ventricular ejection fraction; pyh = pack year history; SNP = single nucleotide polymorphism.
*Genome-wide association study assessed 76 ventricular dysfunction cases; subsequent SNP analyses were successfully validated for 71 of these ventricular dysfunction cases.
†CABG Genomics replication controls include control subjects used in the CABG Genomics validation study.
‡Significantly different between cases and controls (P<0.05).
§Significantly different than other two case groups (P<0.05).

二分变量以百分比（%）形式呈现，连续变量以均值±标准差的形式呈现。
BMI=身体质量指数（body mass index）；CPB=体外循环（cardiopulmonary bypass）；LVEF=左心室射血分数（left ventricular ejection fraction）；pyh=吸烟包年史（pack year history）；SNP=单核苷酸多态性（single nucleotide polymorphism）。
*全基因组关联研究共纳入76例心室功能不全病例；后续针对其中71例该类病例的单核苷酸多态性分析得到了有效验证。
†冠状动脉旁路移植术（Coronary Artery Bypass Graft, CABG）基因组学重复研究的对照对象，包含冠状动脉旁路移植术基因组学验证研究中使用的对照受试者。
‡病例组与对照组间差异具有统计学意义（P<0.05）。
§与其余两个病例组间差异具有统计学意义（P<0.05）。