Genomes of Four Klebsiella pneumoniae isolates

Multi drug resistant Klebsiella pneumoniae will probably to be the next crisis in clinical treatment of infection. Our study aimed to investigate the mechanism of virulence and antimicrobial resistance mechanism through the whole genome sequencing data of 4 clinical isolated string-test positive Klebsiella pneumoniae strains of ESBL or KPC producing.

多重耐药肺炎克雷伯菌（Multi drug resistant Klebsiella pneumoniae）或将成为临床感染治疗领域的下一场危机。本研究旨在通过4株产超广谱β-内酰胺酶（Extended-Spectrum Beta-Lactamases，ESBL）或产肺炎克雷伯菌碳青霉烯酶（Klebsiella pneumoniae carbapenemase，KPC）且黏丝试验（string test）阳性的临床分离肺炎克雷伯菌菌株的全基因组测序数据，探究其毒力与抗菌耐药机制。