Epidemiological profile of patients with congenital and gestational syphilis in a city in the State of São Paulo, Brazil

Abstract Objectives: to assess the epidemiological profile of congenital and syphilis during pregnancy in residents of São José do Rio Preto in São Paulo State. Methods: ecological study of the epidemiological profile of patients with congenital and gestational syphilis, based on the Sistema de Informação de Agravos de Notificação (Information System for Notifiable Diseases) from 2007 to 2016. Results: there were 396 cases of syphilis reported in pregnant women and 290 of congenital syphilis. In 2016, the rate of detecting syphilis in pregnant women was 13.2 cases/1,000 live births, while congenital syphilis the incidence rate was 6.5 cases/1,000 live births. For gestational syphilis, 54% of the diagnosis was performed in 2nd or 3rd trimester and 85% were reported at the primary care. Adequate treatment for pregnant women occurred in 96% of the notifications with 52% of partners treated. In congenital syphilis, 82% of the mothers underwent prenatal care. However, 94% of the pregnant women were treated inadequately while 82% of the partners did not receive any treatment. Conclusions: there has been an increase in the number of cases of gestational syphilis in pregnant women and a decrease in the cases of congenital syphilis from 2014. These results showed that the goal of 0.5 case/1,000 live births proposed by World Health Organization is still far from being achieved in this city.

摘要
研究目的：评估圣保罗州圣若泽杜里约普雷托地区居民的妊娠期梅毒与先天性梅毒的流行病学特征。
研究方法：本研究为生态学研究，基于2007年至2016年法定传染病监测信息系统（Sistema de Informação de Agravos de Notificação，英文全称：Information System for Notifiable Diseases）的监测数据，分析妊娠期梅毒与先天性梅毒患者的流行病学特征。
研究结果：本研究共上报孕妇梅毒病例396例，先天性梅毒病例290例。2016年，该地区孕妇梅毒检出率为13.2例/1000活产儿，先天性梅毒发病率为6.5例/1000活产儿。针对妊娠期梅毒病例，54%的诊断于妊娠中晚期完成，85%的病例由基层医疗卫生机构上报。96%的上报病例对应的孕妇接受了规范治疗，其中52%的患者性伴侣接受了治疗。在先天性梅毒病例中，82%的患儿母亲接受了产前保健服务。然而，仍有94%的孕妇治疗不规范，82%的性伴侣未接受任何治疗。
研究结论：2014年以来，本地区孕妇妊娠期梅毒病例数呈上升趋势，而先天性梅毒病例数则有所下降。本研究结果显示，世界卫生组织提出的0.5例/1000活产儿的防控目标，在该地区仍远未实现。