Enterocyte-specific FATP4 deficiency elevates blood lipids via a shift from polar to neutral lipids in distal intestine

Lipidomics analyses of phospholipids, sphingolipids (ESIMS PL and SPL), and fatty acids (GCMS FA) in intestinal tissues of control and enterocyte-specific Fatp4 knockout mice

针对对照组及肠上皮细胞特异性Fatp4基因敲除小鼠的肠道组织，开展脂质组学（Lipidomics）分析，检测对象包括磷脂（phospholipids, PL）、鞘脂（sphingolipids, SPL）以及脂肪酸（fatty acids, FA）；其中磷脂与鞘脂采用电喷雾电离质谱（Electrospray Ionization Mass Spectrometry, ESIMS）进行检测，脂肪酸则采用气相色谱-质谱联用（Gas Chromatography-Mass Spectrometry, GCMS）进行分析。