The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway

To perform loss-of-function screening of 1,001 tumor suppressor genes, to identify previously unrecognized drivers of anti-tumor immunity through the STING–IFN-β pathway.

本数据集旨在针对1001个抑癌基因 (tumor suppressor genes) 开展功能丧失筛选 (loss-of-function screening)，以通过STING-IFN-β通路 (STING–IFN-β pathway) 发掘此前未被探明的抗肿瘤免疫 (anti-tumor immunity) 驱动因子。