Antidiabetic Activity of Extracts of Terminalia brownii Fresen. Stem Bark in Mice

The dataset from the study on Terminalia brownii evaluates its antidiabetic properties through various experiments. It includes the extraction of the stem bark using 80% methanol, acute toxicity assessments in female Swiss albino mice, and in vitro ?-amylase inhibition tests. In vivo experiments were conducted by inducing diabetes in mice with streptozotocin (STZ) and measuring blood glucose levels and glucose tolerance after administration of the crude extract and its solvent fractions. Additionally, preliminary phytochemical screening identified the presence of bioactive compounds. Statistical analysis was performed to assess the significance of the results, providing insights into the potential therapeutic effects of T. brownii on diabetes management.

本数据集源于针对阔叶榄仁（Terminalia brownii）的相关研究，通过多类实验体系评估其抗糖尿病活性。数据集包含以下实验内容：采用80%甲醇萃取其茎皮、对雌性瑞士白化小鼠开展急性毒性评价、以及体外α-淀粉酶抑制实验。体内实验通过链脲佐菌素（streptozotocin，STZ）诱导小鼠构建糖尿病模型，在施加粗提物及其溶剂分级组分后，检测小鼠血糖水平与葡萄糖耐量。此外，初步植物化学筛选实验确认该提取物中存在生物活性化合物。本研究通过统计学分析评估实验结果的显著性，为解析阔叶榄仁在糖尿病管理中的潜在治疗功效提供了科学见解。