Age- and Sex-Specific Cerebral Blood Flow Atlases Across the Lifespan

All data are provided in NIfTI format, registered to the MNI reference space, with an isotropic resolution of 1.0 mm³. The dataset is organized into two subfolders: “CBF-atlases”, which contains the mean and standard deviation maps of the age- and sex-specific CBF atlases (CBF_[age group]_[sex]_[mean or std].nii.gz, units: ml/100g/min), and “T1w-template”, which includes the corresponding age-specific T1-weighted structural templates (T1w-template-[age group]-brain.nii.gz). The age groups include CH (children), YO (youth), YA (young adults), MA (middle-aged adults), and OA (older adults), while the sex categories consist of Male, Female, and All (combined Male and Female). All images are saved with floating-point values. The original datasets used for atlas generation are available from the corresponding author upon reasonable request.In addition to the age-specific templates, we have generated a common template that serves as a central reference across all age groups. This template was created by applying the same methodology used for the age-specific templates but using the generated age-specific templates as inputs instead of individual T1 images. The common T1w template is publicly available in “T1w-template” folder with name of [T1w-template-Allage-brain.nii.gz]. and the common CBF atlases are publicly available in “CBF-atlases” folder with name of [CBF_Allage_mean.nii.gz].

所有数据均采用NIfTI格式存储，并配准至MNI参考空间（Montreal Neurological Institute），各向同性分辨率为1.0 mm³。本数据集分为两个子文件夹：“CBF-atlases”与“T1w-template”。其中“CBF-atlases”文件夹包含按年龄和性别分组的脑血流量（Cerebral Blood Flow, CBF）图谱的均值图与标准差图，文件命名规则为CBF_[年龄组]_[性别]_[均值或标准差].nii.gz，单位为毫升/100克/分钟；“T1w-template”文件夹则包含对应年龄组的T1加权结构模板，文件命名规则为T1w-template-[年龄组]-brain.nii.gz。年龄组包括CH（儿童组，Children）、YO（青年组，Youth）、YA（青年成年组，Young Adults）、MA（中年成年组，Middle-aged Adults）以及OA（老年成年组，Older Adults）；性别类别分为男性、女性以及全体（合并男性与女性数据）。所有图像均采用浮点数值格式存储。用于生成上述图谱的原始数据集，可根据合理请求向通讯作者获取。除上述年龄特异性模板外，本研究还构建了一套适用于所有年龄组的通用参考模板。该模板沿用年龄特异性模板的生成方法，仅将输入替换为已生成的年龄特异性模板，而非单一个体的T1图像。通用T1加权模板存储于“T1w-template”文件夹中，文件名为T1w-template-Allage-brain.nii.gz；通用CBF图谱存储于“CBF-atlases”文件夹中，文件名为CBF_Allage_mean.nii.gz。