NTDs covered in the review.

Introduction Neglected tropical diseases (NTDs) comprise a group of twenty diverse diseases or conditions that pose significant public health challenges and adversely impact the quality of life of affected individuals. NTDs are characterised by interconnected biological, social, and environmental factors, which complicate their effective management and eradication. Collaborative research, such as transdisciplinary research (TDR) and participatory approaches that engage scientific, societal, and non-academic stakeholders in co-creating action-driven solutions offer promising strategies to address NTDs. These approaches bridge scientific research with community practices, ensuring evidence-based, contextually relevant interventions. Despite their potential, the application of these approaches in addressing NTDs remains underexplored. This scoping review explores the utilisation of TDR and participatory research approaches to address NTD-related challenges. Methods A systematic search was conducted in PubMed, Web of Science, Embase, and CINAHL, following the JBI methodology for scoping reviews. Data extraction and analysis were performed using JBI SUMARI software, focusing on peer-reviewed published literature reporting the use of TDR and participatory approaches in NTDs, with an emphasis on individual and community perspectives. Results The review examined seventeen articles from Africa, Asia, South America, and Australia, highlighting the increasing use of TDR and participatory approaches to address common NTDs such as leprosy, schistosomiasis, rabies, Buruli ulcer, and trypanosomiasis. These approaches engaged diverse stakeholders to develop practical, community-oriented solutions. Key strategies included enhancing public awareness, improving screening programmes, and implementing measures to control NTDs. However, challenges such as fragmented strategies and weak health systems hindered efforts to reduce the burden of NTDs. Conclusion TDR and participatory approaches contribute to a holistic approach in addressing and managing NTD-related challenges by engaging diverse stakeholders and fostering a comprehensive understanding of community needs and on-the-ground realities. The findings demonstrate their effectiveness in translating evidence-informed knowledge into actionable interventions to benefit affected individuals and their communities.引言 被忽视热带病（Neglected Tropical Diseases, NTDs）是一类包含二十余种不同疾病或病症的公共卫生挑战集合，对受影响个体的生活质量造成严重负面影响。此类疾病的发生与生物、社会及环境因素相互交织，这一特性使得其有效管控与根除工作变得复杂棘手。跨学科研究（Transdisciplinary Research, TDR）与参与式研究等协作式研究模式，通过吸纳科学、社会及非学术利益相关方共同参与，共创以行动为导向的解决方案，为应对被忽视热带病提供了颇具前景的策略。这类研究模式搭建起科学研究与社区实践之间的桥梁，确保干预措施具备循证依据且贴合当地实际情境。尽管此类模式潜力巨大，但其在应对被忽视热带病领域的应用仍有待深入探索。本次范围综述旨在探究跨学科研究与参与式研究方法在解决被忽视热带病相关挑战中的应用情况。方法 本研究遵循乔安娜·布里格斯研究所（Joanna Briggs Institute, JBI）的范围综述方法学，在PubMed、Web of Science、Embase及CINAHL数据库中开展系统性检索。研究采用JBI SUMARI软件进行数据提取与分析，聚焦于已发表的同行评议文献，这些文献需报告了跨学科研究与参与式方法在被忽视热带病防控中的应用情况，尤其关注个体与社区视角。结果 本次综述共纳入来自非洲、亚洲、南美洲及澳大利亚的17篇文献，结果显示针对麻风病、血吸虫病、狂犬病、布鲁里溃疡以及锥虫病等常见被忽视热带病，跨学科研究与参与式方法的应用正日益增多。此类研究模式吸纳了多元利益相关方参与，以开发切实可行、以社区为导向的解决方案。核心策略包括提升公众认知、完善筛查项目以及落实被忽视热带病防控措施。然而，碎片化的防控策略与薄弱的卫生系统等问题，仍阻碍了降低被忽视热带病负担的相关工作。结论 跨学科研究与参与式方法通过吸纳多元利益相关方参与，并深化对社区需求与实地现实的全面理解，为应对和管控被忽视热带病相关挑战提供了整体性解决方案。研究结果证实，此类模式可有效将循证知识转化为可落地的干预措施，从而惠及受影响个体及其所在社区。