DMD hiPSCs bifurcate to an alternative branch of the myogenic trajectory

This dataset describes the myogenic trajectory followed by human induced pluripotent stem cells, and the consequences of dystrophin deficiency on the outcome of differentiation Overall design: hiPSCs from two cell lines (Healthy, DMD) were collected at 10 successive time points of the myogenic differentiation and subjected to single-cell combinatorial indexing RNA-Seq (sci-RNA-Seq)

本数据集描述了人类诱导多能干细胞（human induced pluripotent stem cells，hiPSCs）所遵循的肌源性分化轨迹，以及肌营养不良蛋白缺乏对分化结局的影响。实验整体设计：采集两株细胞系的人类诱导多能干细胞（健康型、杜氏肌营养不良症（DMD）），在肌源性分化的10个连续时间点收集样本，并通过单细胞组合索引RNA测序（single-cell combinatorial indexing RNA-Seq，sci-RNA-Seq）进行检测。