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HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 5

NIAID Data Ecosystem2026-05-01 收录

HIV-1蛋白酶抑制剂复合物结构

艾滋病药物设计

数据链接：

https://www.rcsb.org/structure/1B6K 数据链接链接失效反馈

官方服务：

资源简介：

HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 5

与大环肽模拟抑制剂（macrocyclic peptidomimetic inhibitor）5复合的HIV-1蛋白酶

应用场景：

创建时间：

2023-11-15

艾滋病药物设计

整合酶抑制剂

Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design Descriptor: 5-[[[2-[[(1S)-1-(4-METHOXYPHENYL)BUTYL]CARBAMOYL]PHENYL

Protein Data Bank Japan2023-12-20 更新40

HIV-1 Protease WT (NL4-3) in Complex with NR02-79

HIV-1结构解析

艾滋病药物设计

HIV-1 Protease WT (NL4-3) in Complex with NR02-79 Descriptor: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{(2-ethylbutyl)[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl]amino}-3-hydroxy-1-

Protein Data Bank Japan2026-01-07 更新20

Crystal Structure of HIV-1 Reverse Transcriptase in Complex with 5-(cyclopropylmethyl)-7-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-8-methyl-2-naphthonitrile (JLJ678), a Non-nucleoside Inhibitor

艾滋病药物设计

蛋白质复合物结构解析

Protein Data Bank Japan2023-10-18 更新10

Normalized decision matrix NM (BP Case).

艾滋病药物设计

拓扑指数分析

Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. These

Figshare2025-01-17 更新30

Name and sequence of Peptide Nucleic Acid (PNA) targeted against different sites of 5′UTR HIV-1.

艾滋病药物设计

基因靶向治疗

Name and sequence of Peptide Nucleic Acid (PNA) targeted against different sites of 5′UTR HIV-1.

Figshare2015-12-02 更新10