Supplementary Material for: Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania

<b><i>Background/Objective:</i></b> Skin diseases, especially those with visible manifestation, are considered to cause a major influence on global mental health. Therefore, we determined the prevalence and severity of anxiety, depression, and suicidal ideation in a large sample of patients with facial dermatoses, namely acne, rosacea, folliculitis, and perioral dermatitis. <b><i>Methods:</i></b> The mental health of patients with facial dermatoses and respective controls was assessed using the Hospital Anxiety and Depression Scale and questions concerning suicidal ideation. <b><i>Results:</i></b> The study included 543 patients with facial dermatoses and 497 healthy individuals. Anxiety was present in 37.6% of the patients (14.9% of controls), depression in 21.7% (6.8%), and suicidal thoughts in 9.8% (3.2%) (<i>p</i> &lt; 0.001). Acne patients demonstrated the highest anxiety and depression subscale scores (mean ± standard deviation: 7.1 ± 0.25, 95% confidence interval (CI): 6.58–7.56; controls: 5 ± 0.23, 95% CI: 4.57–5.49). In rosacea 30% of the patients had depression symptoms (adjusted odds ratio (OR): 7.216, 95% CI: 4.122–12.632, <i>p</i> &lt; 0.001), while in folliculitis patients 15.4% (OR: 3.138, 95% CI: 1.241–7.936, <i>p</i> = 0.016) had suicidal thoughts. Patients with anxiety symptoms and suicidal thoughts were on average younger than those without (28.3 ± 0.76 vs. 31.2 ± 0.66 years, <i>p</i> = 0.001 and 25.3 ± 0.98 vs. 30.5 ± 0.55 years, <i>p</i> = 0.007, respectively). <b><i>Conclusion:</i></b> Acne and rosacea are associated with anxiety, depression, and suicidal ideation in Lithuanian patients. Younger patients are more prone to report such symptoms than older ones.

<b><i>背景与研究目的：</i></b> 皮肤病，尤其是存在可见临床表现的皮肤病，被认为对全球心理健康造成显著负面影响。为此，我们在涵盖痤疮（acne）、酒渣鼻（rosacea）、毛囊炎（folliculitis）及口周皮炎（perioral dermatitis）的大型面部皮肤病患者样本中，明确了焦虑、抑郁与自杀意念（suicidal ideation）的患病率及严重程度。<b><i>研究方法：</i></b> 采用医院焦虑抑郁量表（Hospital Anxiety and Depression Scale）及自杀意念相关问卷，评估面部皮肤病患者及相应健康对照的心理健康水平。<b><i>研究结果：</i></b> 本研究共纳入543名面部皮肤病患者与497名健康对照个体。患者群体中37.6%存在焦虑症状（对照组为14.9%），21.7%存在抑郁症状（对照组为6.8%），9.8%存在自杀意念（对照组为3.2%）（*p* < 0.001）。痤疮患者的焦虑与抑郁维度得分最高（均值±标准差：7.1±0.25，95%置信区间（Confidence Interval, CI）：6.58–7.56；对照组得分：5±0.23，95%置信区间（CI）：4.57–5.49）。酒渣鼻患者中30%存在抑郁症状（校正比值比（adjusted Odds Ratio, OR）：7.216，95%置信区间（CI）：4.122–12.632，*p* < 0.001）；而毛囊炎患者中15.4%存在自杀意念（比值比（OR）：3.138，95%置信区间（CI）：1.241–7.936，*p* = 0.016）。存在焦虑症状与自杀意念的患者平均年龄均低于无对应症状者（分别为28.3±0.76岁 vs 31.2±0.66岁，*p* = 0.001；25.3±0.98岁 vs 30.5±0.55岁，*p* = 0.007）。<b><i>研究结论：</i></b> 在立陶宛患者群体中，痤疮与酒渣鼻与焦虑、抑郁及自杀意念显著相关。年轻患者相较于年长群体更易报告此类心理症状。