Unraveling the Mechanisms of Propofol-Induced Psychological Dependence: A Multi-Omics Approach Linked to Gut Microbiota in Hippocampal Function

The problem was exacerbated by the expanding market for illicit drugs and the increasing availability of synthetic drugs such as fentanyl. Clinical drug abuse is a problem that requires particular attention, and the potential addictive properties of some drugs and their mechanisms of action are currently unknown, which limits the development and implementation of drug addiction intervention strategies.

非法药物市场持续扩张，加之芬太尼（fentanyl）等合成类药物的可及性不断提升，使得相关问题愈发严峻。临床药物滥用是亟需重点关注的问题，部分药物的潜在成瘾特性及其作用机制目前仍未明确，这一现状制约了药物成瘾干预策略的研发与落地实施。