PanX/Piggy MSAs

MSAs for gene clusters curated with PanX from 350 RefSeq assemblies, and for intergenic region clusters based on 228 E. coli ST131 genome sequences generated with Piggy, used to build the E. Coli PanRG (see paper Colquhoun et al. "Nucleotide-resolution bacterial pan-genomics with reference graphs").

本数据集包含两部分数据：其一为基于350个RefSeq组装基因组、经PanX整理得到的基因簇的多序列比对（Multiple Sequence Alignment，MSA）；其二为基于228株大肠杆菌ST131（E. coli ST131）基因组序列、通过Piggy工具构建的基因间区簇。上述数据用于构建大肠杆菌泛基因组参考图（E. Coli PanRG），相关研究详见Colquhoun等人发表的题为《基于参考图的核苷酸分辨率细菌泛基因组学》的论文。