CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c4(c(C(Nc2cc1nc(cn1cc2)c3ccccc3)=O)n(nc4)C)C(N(C)C)=O, micromolar IC50=0.000153

Protein Data Bank Japan2024-10-16 更新2026-03-21 收录

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CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH c4(c(C(Nc2cc1nc(cn1cc2)c3ccccc3)=O)n(nc4)C)C(N(C)C)=O, micromolar IC50=0.000153 Descriptor: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... Authors: Joseph, C, Benz, J, Flohr, A, Peters, J, Rudolph, M.G. Deposit date: 2022-02-01 Release date: 2022-10-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure of a human phosphodiesterase 10 complex To be published

人类磷酸二酯酶10与配体c4(c(C(Nc2cc1nc(cn1cc2)c3ccccc3)=O)n(nc4)C)C(N(C)C)=O结合的晶体结构，其半最大抑制浓度（IC50）为0.000153微摩尔。描述项：氯离子、甘油、镁离子……作者：Joseph, C、Benz, J、Flohr, A、Peters, J、Rudolph, M.G. 沉积日期：2022-02-01 发布日期：2022-10-12 最后修改日期：2024-10-16 实验方法：X射线衍射（分辨率2.1埃）。引用文献：《人类磷酸二酯酶10复合物的晶体结构》待发表

创建时间：

2022-02-01