RNAseq of soluble factors in RPE cells from Cryba1 conditional knockout (cKO) mice

The study was aimed at understanding the expression of known neutrophil regulating factors in the retinal pigment epithelium (RPE) cells with increasing age in a mouse model (Cryba1 cKO, mice lacking gene which codes for beta A3/A1-crystallin protein only in the RPE cells) of age-related macular degeneration The samples are RPE cells harvested from the mouse eyes from control (Cryba1 floxed/WT) and Cryba1 cKO animals at 5 months and 10 months old