Supplementary Tables S1-13 from Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

Table S1. Cell samples used for CAGE profiling. Table S2. Public datasets used in this study. Table S3. Differentially expressed promoters in FANTOM5 NSCLC cell lines. Table S4. Up-regulated/hypomethylated promoters in NSCLC cell lines. Table S5. Epi-markers in NSCLC. Table S6. Extended information for Table 2. Table S7. Univariate and multivariate Cox regression models of TCGA LUAD and LUSC datasets. Table S8. Gene expression profiling of SAECs treated with 5-aza-dC and TSA. Table S9. Up-regulated/hypomethylated genes in NSCLC cell lines that show up-regulation by 5-aza-dC and TSA in SAECs. Table S10. Promoters and methylation array probes that overlap nine families of repetitive elements. Table S11. Promoters and methylation array probes that overlap REP522 repetitive elements. Table S12. Transcripts commonly down-regulated by two different MYEOV siRNAs in A549 cells. Table S13. The relationship between expression of 22 epi-markers and EGFR/KRAS mutation in TCGA LUAD dataset.

表 S1：用于 CAGE 剖析的细胞样本。表 S2：本研究中使用的公共数据集。表 S3：FANTOM5 非小细胞肺癌细胞系中的差异表达启动子。表 S4：非小细胞肺癌细胞系中上调/低甲基化的启动子。表 S5：非小细胞肺癌中的表观遗传标记。表 S6：表 2 的扩展信息。表 S7：TCGA LUAD 和 LUSC 数据集的单变量和多变量 Cox 回归模型。表 S8：5-aza-dC 和 TSA 处理的 SAECs 的基因表达谱。表 S9：在 SAECs 中由 5-aza-dC 和 TSA 上调的 NSCLC 细胞系中的上调/低甲基化基因。表 S10：与九种重复元素家族重叠的启动子和甲基化阵列探针。表 S11：与 REP522 重复元素重叠的启动子和甲基化阵列探针。表 S12：在 A549 细胞中由两种不同的 MYEOV siRNA 常规下调的转录本。表 S13：TCGA LUAD 数据集中 22 个表观遗传标记的表达与 EGFR/KRAS 突变的关联关系。