AiPD

AiPD is the first curated repository for autoinhibited proteins, standardizing data on 698 experimentally validated autoinhibitory domains (AIDs), 42,520 predicted AIDs, regulatory mechanisms, disease links, and PTMs from 864 studies. It enables sequence analysis for potential AIDs and supports research into allosteric regulation and therapeutic targeting.

AiPD 是首个面向自抑制蛋白的人工整理数据库，标准化收录了来自864项研究的698个经实验验证的自抑制结构域（autoinhibitory domains，AIDs）、42520个预测自抑制结构域、调控机制、疾病关联以及翻译后修饰（post-translational modifications，PTMs）相关数据。该数据库可针对潜在自抑制结构域开展序列分析，为变构调控与治疗靶点研究提供有力支撑。