N-myc regulates lens growth and terminal differentiation in vivo

We performed RNA-seq with both wild type and N-myc knock-out E14 mouse lenses and identified the differentially expressed genes affected by N-myc knockout. Overall design: We have 3 biological replicates for WT controls and 2 biological replicates for N-myc knock-out samples

本研究针对野生型（wild type）与N-myc基因敲除的E14小鼠晶状体样本开展RNA测序（RNA-seq），并鉴定出受N-myc基因敲除影响的差异表达基因。
整体实验设计：野生型对照组设置3个生物学重复，N-myc基因敲除样本组设置2个生物学重复。