DataSheet_1_Recognizing Tumor Origin for Lymphoid Tumor of Unknown Primary via Total-Body PET/CT Scan—Case Report.docx

Localizing the site of tumor origin for patients with lymphoid tumor is fairly difficult before the definitive detection of the primary tumor, which causes redundant imaging examinations and medical costs. To circumvent this obstacle, the emergence of the world’s first total-body positron emission tomography/computed tomography (PET/CT) provides a transformative platform for simultaneously static and dynamic human molecular imaging. Here, we reported a case of lymph node metastasis from an unknown primary tumor, and the primary tumor was detected with the aid of the total-body PET/CT scanner. This patient with right neck mass was subjected to static and dynamic PET scan, as the static PET imaging found irregular thickening of the upper rectal wall and the dynamic PET imaging recognized the associations between the lymph metastasis and the rectal tumor lesions. The diagnosis by the total-body PET/CT was confirmed by pathological examination.

在明确检出原发肿瘤前，对淋巴样肿瘤患者进行肿瘤起源位点定位极具挑战性，这会导致不必要的影像学检查与医疗开支。为破解这一难题，全球首台全身正电子发射断层显像/计算机断层扫描（positron emission tomography/computed tomography，PET/CT）的问世，为同时开展静态与动态人体分子成像提供了革命性技术平台。本研究报道一例原发灶不明的淋巴结转移瘤病例，借助该全身PET/CT扫描仪成功检出原发肿瘤。该患者因右侧颈部肿块就诊，先后接受静态与动态PET扫描：静态PET显像发现直肠上段管壁不规则增厚，动态PET显像则明确了淋巴结转移灶与直肠肿瘤病灶之间的关联。全身PET/CT的诊断结果经病理学检查得以证实。