Main interactions of the PGK1 amino acids involved in the mutations.

aAtomic coordinates of Protein Data Bank entry 2XE7;batomic coordinates of Protein Data Bank entry 2WZC;ccalculated with the CCP4 Suite, residues are considered solvent accessible when accessible surface area is >5 Å2.a. 蛋白质数据银行（Protein Data Bank）条目2XE7的原子坐标；b. 蛋白质数据银行（Protein Data Bank）条目2WZC的原子坐标；c. 相关计算通过CCP4软件套件（CCP4 Suite）完成，当残基的可及表面积大于5 Ų时，该残基被认定为溶剂可及残基。